Aging (or stage) of ischemic stroke is important in a number of clinical settings. Both CT and MRI can help in determining when a stroke occurred. Based on multiple sequences, especially DWI and ADC, MRI has not o...
CytoskeletonMicrogliosisNeuroinflammationTransient ischemic attackWhite matterTransient ischemic attack (TIA) presents a high risk for subsequent stroke, Alzheimer's disease (AD), and related dementia (ADRD). However, the neuropathophysiology of TIA has been rarely studied. By evaluating recurrent TIA-...
is the most common type of stroke (>80%) and is the second leading cause of death, dementia, and disability worldwide.1This condition occurs when a sudden obstruction of the blood supply or a reduction of normal cerebral blood flow (CBF) leads to brain injuries.2The sudden brain tissue d...
It may be due to post-ischemic gliosis in early ischemia after pre-treadmill training. With the ischemic time passing by, GLT-1 expression in the ischemic group showed a gradual decreasing trend, while GLT-1 expression exhibited a marked increasing trend in the pre-treadmi...
Ischemic stroke is a major cause of long-term disabilities, including vision loss. Neuronal and blood vessel maturation can affect the susceptibility of and outcome after ischemic stroke. Although we recently reported that exposure of neonatal mice to hy
The reason may be that hypothermia attenuates gliosis and partially overlays ischemia-induced glial activation. The intensity of GFAP immunoreactivity was significantly increased in the intravitreal treatment eyes, except for the PEDF/Avastin treatment eyes. The PEDF/Avastin treatment eyes showed very ...
protein-1, IL-1β [40], glial fibrillary acidic protein (GFAP), vimentin, and nestin that can lead to reactive gliosis and scar formation [41]. After stroke, due to failure of Na+, K+pump, astrocytes swell, which leads to high intracerebral pressure and less cerebral perfusion [42]....
semiovale and (iii) deep prominent sulci, abutting the ventricle. These findings can be identified on both T1 and T2 weighted imaging. MRI has the advantage that an increased signal intensity on T2 weighted imaging highlights areas of presumed gliosis. Once myelination has occurred, the fluid ...
Collectively, these findings suggest that increased p-TrkB in neurons, as well as enhanced collateral microvasculature and reduced inflammatory gliosis, may be associated with the neuroprotection mechanisms by sEH blockade. The student’s t-test was used to determine the significance of differences in...
ischemic brain injury suggest the commonest lesion is wide- spread WM gliosis (3,6). Placental abruption is an identified antecedent factor (7). Regional differences in vulnerability to HI exist (8,9). Pre- term WM is susceptible to HI, and inflammation due to the selective vulnerability ...