Within the white matter regions, there was a strong negative correlation between mean diffusivity and anisotropy (r=-0.92, P<0.0001). The characteristic pattern found on diffusion tensor imaging in this patient group is consistent with axonal loss and gliosis leading to impairmen...
Brain CT scan without contrast (A) reveals ill-defined low attenuations (thick-arrow) in the left corona radiata and basal ganglia with density slightly lower than white matter, indicating recent ischemic cerebral infarction...
So far only 16 of the 29 surviving infants who had a neonatal MRI have had a repeat scan during the second year of life. A good correlation was found between areas of gliosis in infancy and the cystic lesions seen during the neonatal period. ...
Exposure to HI conditions can result in mild, moderate, or severe injuries in human, rat, and mouse brain56,57,58and mouse and rat retina54,59. While the inner retina (responsible for b-wave) is especially susceptible to various kinds of ischemic conditions, the outer retina (responsible fo...
Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. Brain. 2013;136(Pt 12:3578–88. Article Google Scholar Ma Y, Wang J, Wang Y, Yang GY. The biphasic function of microglia in ischemic stroke. Prog Neurobiol. 2017;157:247–72. Article CAS ...
ischemic brain injury suggest the commonest lesion is wide- spread WM gliosis (3,6). Placental abruption is an identified antecedent factor (7). Regional differences in vulnerability to HI exist (8,9). Pre- term WM is susceptible to HI, and inflammation due to the selective vulnerability ...
protein-1, IL-1β [40], glial fibrillary acidic protein (GFAP), vimentin, and nestin that can lead to reactive gliosis and scar formation [41]. After stroke, due to failure of Na+, K+pump, astrocytes swell, which leads to high intracerebral pressure and less cerebral perfusion [42]....
Finally, changes in imaging profiles between the 5- and 90-day period could provide valuable information regarding the degree of atrophy, gliosis, and volume loss due to infarction, as well as other sequelae such as Wallerian degeneration, cortical necrosis, and/or mineralization (Table 4). The...
Collectively, these findings suggest that increased p-TrkB in neurons, as well as enhanced collateral microvasculature and reduced inflammatory gliosis, may be associated with the neuroprotection mechanisms by sEH blockade. The student’s t-test was used to determine the significance of differences in...
protein-1, IL-1β [40], glial fibrillary acidic protein (GFAP), vimentin, and nestin that can lead to reactive gliosis and scar formation [41]. After stroke, due to failure of Na+, K+pump, astrocytes swell, which leads to high intracerebral pressure and less cerebral perfusion [42]....