Finding the key signaling pathways and influencingfactors has become crucial to prevent hair loss and treat hair loss disorders. In thispaper,the morphological development of hair follicle,hair cycle and important signalpathway(Wnt signal pathway)are reviewed. ...
1.Choi YS, Zhang Y. Distinct functions for Wnt/β-catenin in hair folliclestem cell proliferation and survival and interfollicular epidermal homeostasis.Cell Stem Cell. 2013 Dec 5;13(6):720-33. 2.Nusse R, Clevers H. Wnt/β-Catenin Signaling, Disease, and EmergingTherapeutic Modalities. Cell...
Also, the high expression of Wnt pathway was shown to be highly associated with CD44+/CD133+ colorectal CSCs compared to CD44−/CD133− cells [41]. In skin cancer, Wnt activated in the bulge stem cells (CD34+) of the hair follicle, and β-catenin-deficient tumor cells devoid of ...
1.Choi YS, Zhang Y. Distinct functions for Wnt/β-catenin in hair folliclestem cell proliferation and survival and interfollicular epidermal homeostasis.Cell Stem Cell. 2013 Dec 5;13(6):720-33. 2.Nusse R, Clevers H. Wnt/β-Catenin Signaling, Disease, and EmergingTherapeutic Modalities. Cell...
在深入理解Wnt信号调控机制的同时，科研人员需要设计严谨的临床试验，慎重评估候选药物的功效和毒副作用。期待未来能研发出真正奏效的Wnt激动剂，帮助脱发患者重现“长发”之美。祝我们三十不秃。参考文献：Choi BY. Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss. Int J Mol Sci. 2020 ...
Hair follicle development and related gene and protein expression of skins in Rex rabbits during the first 8 weeks of life Since [beta]-catenin mutations and activated Wnt signaling pathway are found to be closely related with hepatocellular carcinoma (HCC) development and progression, we had previo...
1.Choi YS, Zhang Y. Distinct functions for Wnt/β-catenin in hair folliclestem cell proliferation and survival and interfollicular epidermal homeostasis.Cell Stem Cell. 2013 Dec 5;13(6):720-33. 2.Nusse R, Clevers H. Wnt/β-Catenin Signaling, Disease, and EmergingTherapeutic Modalities. Cell...
0 评论次数: 0 文档热度: 文档分类: 幼儿/小学教育--教育管理 系统标签: 干细胞毛囊wnt定向分化通路信号 硕士学位论文Wnt信号通路介导的基因调控毛囊干细胞定向分化的研究Wntsignalingpathwaymediatedgeneregulatehairfolliclestemcellscommitteddifferentiation所院:广州医学院姓名:***导教师:**教授学科专业:外科学研究方向...
wetrytorevealtherelationshipbetweenWntsignalingpathwayandskinwoundhealingfrominflammatorycells,fibroblasts,stemcell,angiogenesis,epidermisandhairfollicleregenerationandsoon.Keywords:Wntprotein;Wntsignalingpathway;Woundhealing;MechanismChineseLibraryClassification(CLC):R34;R632;Q593Documentcode:AArticleID:1673-6273(2015)11...
最近,华南师范大学生物光子学研究院邢达教授研究团队在Cell Press细胞出版社旗下期刊Stem Cell Reports上发表了一篇题为“Photobiomodulation therapy for hair regeneration: A synergetic activation of β-CATENIN in hair follicle stem cells by ROS and paracrine WNTs”的文章,研究团队在探讨光生物调节疗法(PBMT)...