accumulated studies have proven that the proteins related to the abnormally-activated Wnt signaling pathway are expressed in ovarian cancer. In this article, the latest research progress on
Wnt signaling pathway in cancer immunotherapyYang Zhou a cJiang Xu bHaichang Luo cXiangjing Meng c dMing Chen e Person EnvelopeDi Zhu a c Person EnvelopeCancer Letters
Wnt signaling is a highly conserved signaling pathway that plays a critical role in controlling embryonic and organ development, as well as cancer progression. Genome-wide sequencing and gene expression profile analyses have demonstrated that Wnt signaling is involved mainly in the processes of breast ...
Wnt signaling pathway in cancer immunotherapy. Cancer Lett. 2022;525:84–96. Article CAS PubMed Google Scholar Wang B, Tian T, Kalland KH, Ke X, Qu Y. Targeting Wnt/beta-catenin signaling for cancer immunotherapy. Trends Pharmacol Sci. 2018;39(7):648–58. Article CAS PubMed Google ...
[1] Chu, Hang Yin,et al."Dickkopf-1: A promising target for cancer immunotherapy." Frontiers in Immunology 12 (2021): 658097. [2] Diarra, Danielle,et al."Dickkopf-1 is a master regulator of joint remodeling." Nature medicine 13.2 (2007): 156-163. ...
W. Wnt-related molecules and signaling pathway equilibrium in hematopoiesis. Cell Stem Cell 4, 27–36 (2009). Article CAS PubMed PubMed Central Google Scholar Monga, S. P. Role of Wnt/β-catenin signaling in liver metabolism and cancer. Int. J. Biochem. Cell Biol. 43, 1021–1029 (...
[1] Chu, Hang Yin, et al. "Dickkopf-1: A promising target for cancer immunotherapy." Frontiers in Immunology 12 (2021): 658097. [2] Diarra, Danielle, et al. "Dickkopf-1 is a master regulator of joint remodeling." Nature medicine 13.2 (2007): 156-163. ...
immunotherapy and targeted therapy have achieved good clinical effects in the treatment of non-small cell lung cancer, there are many adverse reactions, drug resistance, recurrence and other problems, and the 5-year survival rate of NSCLC patients is still not ideal. The Wnt/ β-catenin signalin...
Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental cancer models of animals. Aberrant activation of Wnt/β-catenin signaling is tightly linked with the increment of prevalence, advancement of malignant progression, dev
1 However, breast cancer is a complex, heterogeneous disease characterized by a great multitude of aberrations at the genomic and molecular level, which can manifest in dysregulated signaling pathways. A hallmark of many cancers is aberrant regulation of the Wnt signaling pathway, and breast cancer ...