6.Geeraerts SL, Kampen KR, Rinaldi G, et al. Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth. Mol Cancer Ther. 2021;20(1):50-63. 7.Pacold ME, Brimacombe KR, Chan SH, et al. A PHGDH inhibitor reveals coordinati...
Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth. Mol Cancer Ther. 2021;20(1):50-63. 7.Pacold ME, Brimacombe KR, Chan SH, et al. A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. ...
NCT-503磷酸甘油酸脱氢酶(PHGDH)抑制剂,IC50值为2.5μM。注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!CAS号:1916571-90-8纯度:98.40%分子式:C20H23F3N4S分子量:408.48结构式:储存条件:-20℃,有效期2年,溶入溶剂后-20℃请尽量在一个月内使用。相关搜索:磷酸甘油酸脱氢酶(PHGDH)抑制剂(NCT-503),...
英文名称:3-Phosphoglycerate dehydrogenase inhibitor 产品规格:1mL(10mM)|5mg|10mg|25mg|50mg|100mg CBR-5884是PHGDH的抑制剂,IC50是33uM,能够在癌症细胞中减少丝氨酸合成,能够抑制癌细胞的扩散和扰乱PHGDH的低聚状态。 注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!
PHGDH抑制剂(CBR-5884) 更多供应商 上海泽叶生物科技有限公司 联系电话: 021-61998551 13122364865 产品介绍: 中文名称:PHGDH抑制剂(CBR-5884) 英文名称:3-Phosphoglycerate dehydrogenase inhibitor 纯度:99.9% 包装信息:5mg/ 最新发布供应信息 PHGDH抑制剂(CBR-5884)询价上海泽叶生物科技有限公司2024/11/29 ...
A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. Nature Chemical Biology. 2016.Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, Cho S, Freinkman E, Birsoy K, Abu-Remaileh M, Shaul...
英文名称:3-Phosphoglycerate dehydrogenase inhibitor 产品货号:M00437 产品规格:1mL(10mM)|5mg|10mg|25mg|50mg|100mg CBR-5884是PHGDH的抑制剂,IC50是33uM,能够在癌症细胞中减少丝氨酸合成,能够抑制癌细胞的扩散和扰乱PHGDH的低聚状态。 注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!
1-Piperazinecarbothioamide, N-(4,6-dimethyl-2-pyridinyl)-4-[[4-(trifluoromethyl)phenyl]methyl]-; CS-2612; NCT 503; NCT503.; 9-(6-aminopyridin-3-yl)-1-(4-fluoro-3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one; NCT-503; inhibit,NCT-503,NCT503,Inhibitor; ...
今天和大家分享一篇发表在Acta Pharmaceutica Sinica B 上的一篇文章Identificationof a novel PHGDH covalent inhibitor by chemical proteomics and phenotypicprofiling 。文章的通讯作者是来自中国药科大学的孔令义教授,他的研究方向包括中药和天然...
参考文献:Chen C, Zhu T, Liu X, Zhu D, Zhang Y, Wu S, Han C, Zhang H, Luo J, Kong L. Identification of a novel PHGDH covalent inhibitor by chemical proteomics and phenotypic profiling. Acta Pharm Sin B. 2022 Jan;12(1):246-261. doi: 10.1016/j.apsb.2021.06.008. Epub 2021 Jun...