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Next, we used Module-Trait Relationships (MTRs) from WGCNA package to determine the significant correlation between module eigengene and BRCA traits (subtypes) classified by TCGA database. For intramodular analysis, we evaluated the Gene Significance (GS) and Module Membership (MM), the latter of ...
3.4. Calibration Calibration is the process of classifying conditions from full membership to full non-membership. Using the method described by Ragin [71], we defined three different anchors to calibrate the data to establish the degree of membership in each score: 0.95 for full membership, 0.50...