other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. ...
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. 基因名: TGFBR3 别名: BGCAN,betaglycan 基因ID: 7049 Chromosome:(GRCh37) 1 Start: 92145902 End: 92371892 Strand: -1 信号通路: TGFBR3 基因突变与药物 TGFBR3...
另外,编码不同亚型的剪接转录变体已被鉴定为该基因。 This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces solubl...
Gene ID: 7049 种属 Homo sapiens 基因DNA序列编号: NM_003243.5 基因DNA描述 Homo sapiens transforming growth factor beta receptor 3 (TGFBR3), transcript variant 1, mRNA DNA编码区: atgacttcccattatgtgattgccatctttgccctgatgagctcctgtttagccactgca ggtccagagcctggtgcactgtgtgaactgtcacctgtcagtgcctcccatcctgt...
Association Analysis of TGFBR3 Gene with Vogt-Koyanagi-Harada Disease and Behcet’s Disease in the Chinese Han Population[J] . Yuanyuan Chen,Peizeng Yang,Fuzhen Li,Shengping Hou,Zhengxuan Jiang,Qinmeng Shu,Aize Kijlstra.Current Eye Research . 2012 (4)...
进步对Hv SIAH1研究我们发现,Hv SIAH1在盐胁迫及ABA处理的大麦幼苗中显著上调表达,体外泛素化实验显示Hv SIAH1具有E3连接酶活性,亚细胞定位实验表明Hv SIAH1分布在整个细胞中,利用VIGS(Virus-induced gene silencing)沉默花30中Hv SIAH1后,沉默植株在盐胁迫下第4片叶子凋亡,而对照植株生长正常。这些结果表明,E3连接...
早发性卵巢功能不全与TGFBR3基因多态性的相关性 新疆医科大学第一附属医院The correlation between early-onset ovarian insufficiency of women and their TGFBR3 gene polymorphism The First Affiliated Hospital of Xinjiang Medical University,Wulumuqi, Xinjiang, 830054...
TGFBR3 gene expression did not differ between groups. Conclusion We demonstrated that activation of TGF-β signaling is higher in patients with a DN than an HI FBN1 gene mutation. Also, TGFBR3 protein expression is increased in the DN group and correlates positively with TGFB1 expression in ...
(RPKM value in TGF-β2-stimulated-Caki-1-shTGFBR3 #B cells) >5 and (RPKM value in TGF-β2-stimulated-Caki-1-shTGFBR3 #B cells)/(TGF-β2-stimulated Caki-1-shNTC cells) >2. (Top) The red diagram shows gene clusters screened by criteria (i). The blue diagram shows gene ...
Rearrangements and abnormal expression of the TGFBR3 gene – also known as BGCAN or betaglycan – are frequent in some fibroblastic and fibrolipomatous sarcomas and are also found in multiple myeloma and many other malignancies, including breast, colorectal, hepatocellular, oral, lung, prostate, ...