STEM CELL BIOLOGY: STRUCTURE AND FUNCTION | Epigenetic Regulation of Stem CellsEmbryonic stem cells (ESCs) are pluripotent, self-renewing cells that differentiate into specialized cell types in response to developmental cues. The unique ability of ESCs to proliferate while retaining pluripotency is ...
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Thus plant stem cells depend on the function of other, neighboring, cells to continue behaving as stem cells, and therefore some sort of signal must be passed between cells to maintain stem cell behavior. In animals, the signaling molecules used within stem cell niches are often the same used...
Stem cells are characterized by their ability to self-renew and differentiate into many different cell types. Research has focused primarily on how these processes are regulated at a transcriptional level. However, recent studies have indicated that stem
2024年8月23日,加州大学圣地亚哥分校孙欣实验室在Cell Stem Cell杂志在线发表了题为“Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells”的研究论文。该研究揭...
2024年4月30日,美国南加州大学凯克医学院博徳干细胞研究所李中伟组在Cell Stem Cell杂志上发表报道一种新的二维培养方法,通过小分子化合物调控p38和YAP信号通路,实现长期体外扩增培养原代小鼠肾单元祖细胞,人原代肾单元祖细胞及人多能干细胞...
et al. In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells. Blood 80, 3044-3050 (1992). 3 Cabezas-Wallscheid, N. et al. Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy. Cell 169, 807-823.e819, doi:10.1016/j.cel...
The miraculous stem cell is the body's dreamer – it can grow up to be whatever it wants to be. They are unspecialized cells that divide frequently and can become specialized cells depending on the body’s needs. Fun hands-on way to learn about biology, health and these pluripotent myriad...
Single-cell sequencing in stem cell biology 在哺乳动物早期胚胎中只有少量多能干细胞;组织特异性干细胞通常只有少量存在于特殊的组织和...
CELLS, a peer reviewed journal published monthly, provides a forum for prompt publication of original investigative papers and concise reviews. STEM CELLS is read and written by clinical and basic scientists whose expertise encompasses the rapidly expanding fields of stem and progenitor cell biology. ...