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ECASS II, andATLANTIS(Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke), ...
Alteplase for stroke: money and optimistic claims buttress the "brain attack" campaign {#article-title-2}Both doctors and the public are becoming more alert to potential conflicts of interest, and an increasing number of journals now require competing interest statements from their authors and...
Intravenous tissue-type plasminogen activator for treatment of acute stroke: The standard treatment with alteplase to reverse stroke (STARS) Study (STARS). JAMA 2000; 283: 1145–1150. CrossRef Katzan I, Furlan A, Lloyd L, Frank J, Harper D, Hinchey J, Hammel J, Qu A, Sila C. Use ...
Alteplase for stroke: money and optimistic claims buttress the "brain attack" campaign {#article-title-2}Both doctors and the public are becoming more alert to potential conflicts of interest, and an increasing number of journals now require competing interest statements from their authors and ...
All eligibility criteria from the National Institute of Neurological Disorders and Stroke (NINDS) recombinant tPA Stroke Study were adopted within the alteplase package insert as contraindications/ warnings. Many clinicians have expressed the need for clarification and better definition of these treatment ...
We re-examined the effect of time to treatment with intravenous rt-PA (alteplase) on therapeutic benefit and clinical risk by adding recent trial data to the analysis. Methods We added data from ECASS III (821 patients) and EPITHET (100 patients) to a pool of common data elements from six...
AlteplaseThe NINDS rt-PA Stroke Study is frequently cited in support of alteplase for acute ischemic stroke within 3h of symptom onset. Multiple post-hoc reanalyses of this trial have been published to adjust for a baseline imbalance in stroke severity. We performed a risk of selection bias ...
Alteplase for stroke: money and optimistic claims buttress the "brain attack" campaign {#article-title-2}Both doctors and the public are becoming more alert to potential conflicts of interest, and an increasing number of journals now require competing interest statements from their authors ...