Manco Inca Yupanqui)Also found in: Encyclopedia, Wikipedia. Related to Manco Inca Yupanqui: Manco Capac, Tupac AmaruMan·co Ca·pac 1 (mäng′kō kä-päk′) fl. 12th century. Legendary founder of the Inca dynasty who established Cuzco as the center of what would later become the ...