Treatment of JMML other than stem cell transplantation: A retrospective analysis of 129 treatment courses in 63 patientsHIVp24CD4CD8ICAMVCAMplacentaBACKGROUND: The aim of this study was to compare histomorphometric changes and the results of immunohistochemical tests for VCAM, ICAM-1, CD4 and CD8 ...
Pulsipher, M., Adams, R., Asch, J.et al.Successful treatment of JMML relapsed after unrelated allogeneic transplant with cytoreduction followed by DLI and interferon-alpha: evidence for a graft-versus-leukemia effect in non-monosomy-7 JMML.Bone Marrow Transplant33, 113–115 (2004). https://...
Relapse is the major cause of treatment failure after allogeneic transplantation of children with juvenile myelomonocytic leukemia (JMML), and the role of post-transplant immunomodulation is poorly understood. We report a 12-month-old child with JMML relapsed after unrelated marrow transplantation who re...
28.将步骤2中外周血或骨髓液中获得dna利用covaris超声打断仪(covaris,s220)按照参数peakincidentpower175w、dutyfactor10%、cyclesperburst200、treatmenttime180s片段化至200bp左右。 29.b.末端修复、连接接头按照2000:1的比例在片段化dna中加入lambdadna后使用rapidmaxdnalibprepkitforillumina(abclonal,rk20217)试剂盒进...
[8]Niemeyer,C.M.&Kratz,C.P.Paediatricmyelodysplasticsyndromesandjuvenilemyelomonocyticleukaemia:molecularclassi?cationandtreatmentoptions[J].BrJHaematol,2008,140(6):610–624. [9]SankaranVG,MenneTF,XuJ,AkieTE,LettreG,VanHandelB,etal.HumanFetalHemoglobinExpressionIsRegulatedbytheDevelopmentalStage-SpecificRep...
(GM-CSF).JMML diagnosis should be considered in infants or children with fever, hepatosplenomegaly, lymphadenopathy, rash and/or hemorrhage, accompanied by mononucleosis, hemocytopenia and/or dysplastic cells in the circulation.The choice of treatm...
[4] 绝大多数JMML常伴有外周血白细胞计数增加、血小板计数减少和肝脾肿大,一般不难诊断,但如临床表现隐匿,无明显肝脾肿大者,常误诊为血小板减少性紫癜、继发感染等病症。本文报道一例疑难JMML,经血红蛋白电泳后发现胎儿血红蛋白(Fetal haemoglobin,HbF)异常升高后及时明确了诊断,并经两次同胞间造血干细胞移植术后...
[1]Hasle H.Myelodysplastic syndromes in childhood--classification, epidemiology, and treatment. Leukemia & Lymphoma, 1994, 13(1-2):11-26. [2]Emanuel PD.Juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia. Leukemia...
Methods The characteristics of acute myelomonocytic leukemia complicated with massive intravascular hemolysis due to sepsis and its treatment were discussed with review of literatures. 方法报道1例急性粒-单核细胞白血病并发感染性急性血管内溶血的诊断及治疗经过,并复习相关文献。 更多例句>> 6) Acute myelomono...
Fenaux P, Mufti GJ, Hellstrom-Lindberg E et al (2009) Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 10:223–232 ...