These three factors function collaboratively in an auto-regulatory circuitry fashion to maintain their own expression and maintain the pluripotency of ES cells[106,114]. Additionally, Nanog was identified as the key factor, which regulates the establishment of the pluripot...
The antibody variants thus generated are displayed in a monovalent fashion from filamentous phage particles as fusions to the gene III product of M13 packaged within each particle. The phage-displayed variants are then screened for their biological activity (e.g., binding affinity) as herein ...