In HF with reduced ejection fraction (HFrEF), also known as systolic HF, the heart muscle is not able to contract adequately and, therefore, expels less oxygen-rich blood into the body. Patients with this form of the disease will have lower-than-normal left ventricular ejection fraction on ...
结果显示: 1.与HFrEF患者和非HF对照组相比,HFpEF患者生活质量更差,焦虑评分升高(6.5 ± 3.2 vs. 3.3 ± 2.8 vs. 3.8 ± 2. 8, P = 0.02),抑郁评分升高(6.5 [3.5–10.0] vs. 3.0 [1.0–6.5] vs. 2.0 [0.75–3.0], P = 0.01)。...
In HF with reduced ejection fraction (HFrEF), also known as systolic HF, the heart muscle is not able to contract adequately and, therefore, expels less oxygen-rich blood into the body. Patients with this form of the disease will have lower-than-normal left ventricular ejection fraction on ...
在针对心力衰竭类型预先计划的分析中:HFrEF患者,Shunt组与安慰剂组相比,年度事件率显示出显著差异(49.0% vs. 88.6%,相对风险[RR] 0.55),而在HFpEF的患者中,Shunt组的事件率却更高(60.2% vs. 35.9%,RR 1.68)。接受分流器的HFrEF患...
These results demonstrate that HFrEF and HFpEF are distinct vascular entities, and the changes in protein expression contribute to the vascular abnormalities associated with these diseases. Further in HFpEF, the decrease in MYPT1 would explain why pharmacologic therapies that are designed to activate ...
HFpEF组与HFrEF组中从基线到剂量滴定结束时心率减慢的幅度相当(6.6次/分 vs. 6.9次/分),但不同的是,HFpEF组收缩压的下降幅度明显大于HFrEF患者(14.3 mmHg vs. 7.5 mmHg),其N-末端尿钠肽原(NT-proBNP)水平显示出升高,而HFrEF患者的NT-proBNP水平基本无变化。
导管消融术能够降低心房颤动(AF)合并射血分数降低型心力衰竭(HFrEF)患者的心衰住院和死亡率。然而,在射血分数保留的心力衰竭(HFpEF)患者中,其益处仍不明确。近期,JAMA Cardiology杂志发表了一项研究,旨在探索导管消融术是否能根据心力衰竭表型减少与心力衰竭相关的不良结局。一起来看看吧!
RELIEVE-HF试验是第一个关于心房间分流的随机安慰剂对照试验,其中包括两种类型的心力衰竭患者:射血分数降低的心力衰竭(heart failure with reduced ejection fraction,HFrEF)和射血分数保留的心力衰竭(heart failure with preserved ejection fraction,HFpEF)。研究人员表示,虽然该试验没有达到其主要终点,但它表明房间分流...
HFpEF、HFmrEF和HFrEF的临床特征及左心室重塑对比分析,目的:探讨射血分数保留的心衰(HFpEF)、射血分数中间范围的心衰(HFmr EF)和射血分数下降的心衰(HFr EF)患者临床特征及左心室重塑的差别。方法:选取2013年2月1日至2016年12月31日在我院心内住院的308名心力...
结果:HFpEF组为123例(39.9%),HFmr EF组为98例(31.5%),HFr EF组为88例(28.6%);其中HFpEF组女性比例高于HFr EF组(59.4%vs.38.6%,P〈0.05),高血压和房颤患病率HFpEF组高于HFr EF组(P〈0.05);HFpEF组左心室重构类型以向心性重塑为主,HFr EF组则以离心性重塑为主;HFmr EF组女性比例及高血压,房颤患病率...