The main function of glutamate as a neurotransmitter is to transmit information important for brain development and functioning. It should ideally be present in the right amounts in the right concentrations on the right brain parts for proper functioning. 谷氨酸钠具有强烈的肉类鲜味,味精用水稀释至3000...
Glutamate interaction with specific taste cells in the tongue is a major component of umami taste. The finding of glutamate receptors throughout the gastrointestinal tract has opened up a new vista in glutamate function. Glutamate is truly a functional amino acid. 展开 ...
Both function as very slow transporters with turnover times of 300 msec or longer (this is the length of time it takes to move a single molecule of glutamate across the membrane), but gate fairly large Cl− -currents (Gameiro et al., 2011; Leary et al., 2007; Mim et al.,...
Bergmann gliacerebellumGLASTnitric oxidenNOSBergmann glia (BG) predominantly use glutamate/aspartate transporters (GLAST) for glutamate uptake in the cerebellum. Recently, nitric oxide (NO) treatment has been shown to upregulate GLAST function and increase glutamate uptake in vitro. We previously ...
while CaMKII regulates the function of RyR2 and SERCA2a,4,5,10,23we analyzed the oxidation of these three Ca2+-handling proteins. As shown in Fig.3a–f, administration of glutamate dramatically increased the oxidation of the three Ca2+-handling proteins without significantly changing their total ...
[68–70]. While quiescent center cells are physiologically indistinguishable from the adjacent, actively dividing cells, they have altered mitochondrial function[71]. The addition of GSH or ascorbate stimulates the cells in the quiescent center to progress from the G1 to the S phase of the cell...
GRIA2 (redirected fromglutamate receptor 2) GRIA2 A gene on chromosome 4q32.1 that encodes a member of the excitatory neurotransmitter glutamate receptor family, which are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) and function as ligand-activated cation channels. ...
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16.A giutamate transporter in retinal Muller cells and its function modulation视网膜Müller细胞谷氨酸转运体及其功能调节 17.Regulation of GLAST in Retinal Müller Cells of Mice by BDNF;BDNF对鼠视网膜Müller细胞谷氨酸转运体GLAST的调控 18.Glutamate transporters in central nervous system中枢神经系统谷氨酸转运...
Glutamate’s function as an excitatory neurotransmitter in the brain arises from its ability to initiate action potentials by depolarizing postsynaptic neurons [7,8]. Glutamate’s excitatory function allows for many roles in the brain, including constructing neural connections and networks, synaptic ...