Google Share on Facebook glipizide Thesaurus Medical Wikipedia glip·i·zide (glĭp′ĭ-zīd′) n. A sulfonylurea drug, C21H27N5O4S, used to treat type 2 diabetes. [gli-,pref. for drugs used to control hyperglycemia(variant ofgly-; seeglyburide) + alteration of py(ra)z(ine) +(am...
It is generally well tolerated and categorized as Biopharmaceutics Classification System (BCS) class II drug due to poor water solubility and good permeability. Various analytical methods have also been reported for determination of glipizide in biological fluids. The present article provides a ...
Glipizide (CAS NO.29094-61-9) is an oral medium-to-long acting anti-diabetic drug. View all 4.3 Toxicity LD50 in mice, rats (g/kg): >3, 1.2 i.p. (Ambrogi)5. MSDS2.Hazard identification 2.1 Classification of the substance or mixture Not classified. 2.2 GHS label elements, ...
A solid self-nanoemulsifying drug-delivery system (solid SNEDDS) has been explored to improve the solubility and dissolution profile of glipizide. SNEDDS preconcentrate was systematically optimized using a circumscribed central composite design by varying Captex 355 (Oil), Solutol HS15 (Surfactant) and...
On the basis of solubility, drugs are classified into four classes of the BCS classification. Solubility challenges are faced in the Class II and Class IV of the BCS system. To improve solubility and bioavailability of poorly soluble drug we use various methods or techniques. The methods like ...