Gliosis is a reaction of the CNS to injury of the brain or spinal cord. Although subtle changes occur earlier, gliosis is usually appreciated by 2–3 weeks after an injury. Nearly any injury of the CNS can cause gliosis, so its presence is not diagnostic of a specific pathologic entit...
Transient ischemia in the whole brain leads to neuronal loss/death in vulnerable brain regions. The striatum, neocortex and hippocampus selectively loose specific neurons after transient ischemia. Just 5 minutes of transient ischemia can cause pyramidal neuronal death in the hippocampal cornu ammonis (...
Margerison JH, Corsellis JA (1966) Epilepsy and the temporal lobes: a clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes. Brain 89:499–530 Article CAS PubMed Google Scholar Blümcke I, Thom M, Aronica E ...