days before genetic modification with GFP or GDNF gene. Rat models of Parkinson disease established by stereotactic injection of 6-hydroxy dopamine in the ventral area of the midbrain and the medial forebrain bundle were randomized into 3 groups to receive PBS injection, GFP gene-modified mNSCs t...
Kazuhiko,Kiminori N,Takashi T, et al.BDNF gene-modifiedmesenchymal stem cells promote functional recovery ang reduce infarctsize in the rat middle cerebral artery occlusion model. MolecularTherapy . 2004BDNF gene-modifiedmesenchymal stem cells promote functional recovery and reduce infarctsize in the ...
研究人员Grant 补充说道:“接受这种基因治疗的猴子开始永久提高多巴胺,并且大大减少了饮酒量。这种治疗手段确实通过手术永久性地改变了大脑,因此仅限于那些患有最严重的酒精使用障碍的人。” The monkeys that were treated with this gene permanently started overexpressing dopamine and they decreased their drinking su...
基因序列:NCBI_Gene:25453 蛋白序列: UniprotKB:A7UGI9 UniprotKB:A7UGJ1 UniprotKB:F8WFL7 UniprotKB:Q07731 大鼠Rat Gdnf 靶点分子功能(预测) Enables protein homodimerization activity and signaling receptor binding activity. Involved in several processes, including animal organ development; cellular response to...
关键词GDNF;BMSCs;缺氧复氧;神经细胞;共培养中图分类号R741.05文献标识码A文章编号1000—2669(2011)5—0552—04EXPERIMENTALRESEARCHoNCo—CULTIVATIoNoFBoNEMARRoWMESENCHYMALSTEMCELLSMoDIF皿DBYGDNFGENEANDNEURoNSSUBJECTEDTOANoXIA—REoXYGENATIoNXiongHuailin,etalDepartmentofHumanAnatomy,LuzhouMedicalCollegeAbstractObjective:...
GDNF基因修饰的骨髓基质干细胞移植治疗大鼠脑出血
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Gene: Name:GDNF Protein synonyms/aliases: Glial cell line-derived neurotrophic factor precursor (Astrocyte-derived trophic factor 1) (ATF-1). Protein Family: Belongs to the TGF-beta family. GDNF subfamily. 售后服务 相关视频 资料下载 快速...
The GDNF-TAT gene with TAT gene site and XbaⅠ restriction enzyme sites and α-factor of pPICZαA were obtained by PCR and subcloned into the pPICZαA vector. 1kb和432bp片段,表明目的片段已插入载体中,经序列测定其含有完整的GDNF-TAT基因片段,Western印迹结果显示含有pPICZαA-GDNF-TAT的毕赤酵母...
保存条件 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. 背景资料 GDNF,Glial cell-derived neurotrophic factor,is a protein that,in humans,is encoded by the GDNF gene.GDNF is a small protein that potently promotes ...