Fifty-four mutation carriers were identified among 121 screened relatives. The phenotype consisted of left ventricular dilation (68%), systolic dysfunction (46%), and myocardial fibrosis (67%); inferolateral negative T waves and low QRS voltages on electrocardiography (33%); ventricular arrhythmias ...
Define FLNC. FLNC synonyms, FLNC pronunciation, FLNC translation, English dictionary definition of FLNC. Noun 1. FLNC - a terrorist group formed in 1976 to work for Corsican independence; attacks on Corsica are aimed at sabotaging public infrastructure a
Splicing mutationRecent achievements in the genetic diagnosis of Dilated Cardiomyopathy (DCM) have disclosed rare variants in numerous genes encoding different types of myocardial proteins. However, the causative gene underlying the pathogenesis of about 60% of familial cases with DCM has not been ...
This is the third reported mutation in FLNC in a MFM family with an atypical clinical and histopathological presentation, given the presence of significantly focal lesions and prominent sarcoplasmic masses in muscle biopsies and the constant heart involvement preceding significantly the onset of the ...