tumourclinicallymphocytesIn a recent study published in Nature,Chou and colleagues define a new evolutionarily conserved class of tumour-elicited immune response mediated by a distinct population of T cell receptor(TCR)-positive FCER1G-expressing innate-like T cells with high cytotoxic potential(αβIL...
3Chou and colleagues next compared paired-TCR sequences from tumour-resident NK1.1+CD8α+αβILTCKs and conventional PD-1+CD8α+T cells (PD-1+T cells). From these analyses they could unequivocally conclude that these two tumour infiltrating T cell subsets do not originate from a...
Novel Adenovirus-Based Vaccines Induce Broad and Sustained T Cell Responses to HCV in Man Currently, no vaccine exists for hepatitis C virus (HCV), a major pathogen thought to infect 170 million people globally. Many studies suggest that host T ... E Barnes,A Folgori,S Capone,... - ...