If dystonia symptoms appear in childhood, they usually involve your foot or hand. But then they progress to the rest of the body. After the teen years, though, the symptoms tend to level off. When dystonia appears in early adulthood, it typically begins in your upper body. Symptoms take a...
In primary (isolated) dystonia the dystonic symptoms, which reflect the impairment of the motor system function, are the only disease's manifestation. Primary dystonia is the most prevalent form of dystonia syndrome, with a prevalence of about 16 per 100,000 in general population (Steeves, Day,...
In DYT11 dystonia (myoclonus-dystonia syndrome), myoclonus may predominate, and symptomatic control is sometimes achieved by treating the myoclonus. Data is limited by a small number of reported patients and limited number of controlled trials. Given the subcortical origin of the myoclonus, it is r...
Long-term deep brain stimulation in dystonia: the relationship between effects on electrophysiology and clinical symptoms. Brain 134, 2106–2115 (2011). Article PubMed Google Scholar Tinazzi, M. et al. Aristotle’s illusion reveals interdigit functional somatosensory alterations in focal hand ...
In some individuals, symptoms of a dystonia appear in childhood, approximately between the ages of 5 and 16, usually in the foot or in the hand. In generalized dystonia, the involuntary dystonic movements may progress quickly to involve all limbs and the torso, but the rate of progression usu...
Impaired sleep quality was found in 44% of CD patients, 46% of BL patients, and 20% of controls. In dystonia, it was associated with symptoms of depression (frequency of 26%; p < 0.001) and restless legs syndrome (RLS) (frequency of 19%; p < 0.01). Bruxism (in CD; p < 0.05)...
Nocturnal journey of body and mind in Parkinson's disease: the manifestations, risk factors and their relationship to daytime symptoms. Evidence from the N... Nocturnal manifestations of Parkinson's disease (PD) are myriad, have diverse etiologies and include motor, sleep, urinary, and neuropsychia...
Congenital dopa-responsive disorders are heterogeneous conditions characterized by a relief of clinical symptoms with the administration of levodopa and/or dopaminergic agents. Genetic etiologies classically include defects of dopamine synthesis related to mutations in GCH1 (MIM:128230), TH (MIM:605407),...
Trenkwalder, C, Hening, WA, Walters, AS, Campbell, SS, Rahman, K, Chokroverty, S (1999) Circadian rhythm of periodic limb movements and sensory symptoms of restless legs syndrome. Mov Disord 14: pp. 102-110Merello, M, Nouzeilles, MI, Kuzis, G, Cammarota, A, Sabe, L, Betti, O...
The article presents the case study of a patient with symptoms of dopa-responsive dystonia (DRD) caused by deficiency GTP cyclohydrolase 1. Medical screening of the patient showed brisk deep-tendon teflexes in the legs, which can be mistaken for a positive Babinski sign. Dystonia without ...