Cook GE, Sasich LD, Sukkari SR. Atrial fibrillation. DIONYSOS study comparing dronedarone with amiodarone. BMJ (Clin Res ed.). 2010;340:c285.Cook GE, Sasich LD, Sukkari SR. Atrial fibrillation. DIONYSOS study comparing dronedarone with amiodarone. BMJ. 2010;340:c285....
Antiarrhythmic agents, class I or III (e.g., amiodarone, disopyramide, dofetilide, flecainide, propafenone, quinidine, sotalol) Potential risk of torsades de pointes-type ventricular tachycardia due to QT-interval prolongation Concomitant use contraindicated Anticoagulants, oral (e.g., warfarin) ...
No significant difference was observed in the sinus rhythm maintenance rate between the D-R group and the A-R group (26.8% vs. 22.0%, P =0.43).Compared to co-administration of amiodarone and rivaroxaban, co-administration of dronedarone and rivaroxaban increases the risk of CRNMB but it ...
Dronedarone is a multichannel blocker with electrophysiologic effects similar to amiodarone. Dronedarone has been documented to prevent atrial fibrillation... GV Naccarelli,DL Wolbrette,S Samii,... - 《Journal of Cardiovascular Pharmacology & Therapeutics》 被引量: 21发表: 2010年 A Review of the ...
Food and Drug Administration for the treatment of patients with atrial fibrillation (AF) as a safe alternative to amiodarone. There are no full-length published reports describing the effectiveness of acute dronedarone use against AF in experimental or clinical studies. The purpose of this study was...
A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibril- lation: the DIONYSOS study. J Cardiovasc Electrophysiol 2010;21:597-605....
However, the risk of proarrhythmia, only modest efficacy, and the risk of organ toxicity (amiodarone) have complicated antiarrhythmic drug therapy. In a recent meta-analysis ( 6 ), Vaughan-Williams Class 1A antiarrhythmic agents like quinidine and disopyramide were associated with a > 2-fold ...
The unadjusted HR of ARF was 0.34 (0.18–0.64) in dronedarone new users compared to amiodarone; in propensity score matched cohort, it was 0.75 (0.26–2.16), and in high-dimensional propensity score, it was 0.83 (0.25–2.73). Conclusions This large community-based study did not confirm the...
AmiodaroneRivaroxabanHemorrhageTo investigate whether co-administration of antiarrhythmic dronedarone and anticoagulant rivaroxaban would increase the risks of hemorrhage after atrial fibrillation (AF) ablation.A total of 100 patients with AF who underwent radiofrequency catheter ablation (CA) in the Department...
BARQUET P.DIONYSOS study results showed the respective pr-ofiles of dronedarone and amiodarone.http://en.sanofi-aventis.com/press/press_relea-ses/2008/ppc_23625.asp. 2009DIONYSOS study results showed the respective pr-ofiles of dronedarone and amiodarone. BARQUET P. http://en.sanofi-aventis...