DPP-4抑制剂不仅能双向控制血糖,且具有降糖外的胰腺,心血管,肾脏,肝脏等多器官保护作用和抗炎作用.本文对已有的DPP-4抑制剂及其多器官保护作用进行综述,总结其优势及进一步发展的趋势,为临床用药提供参考.%Dipeptidyl peptidase Ⅳ (DPP-4) inhibitors are a new type of oral antidiabetic drugs appeared in ...
[3]RizzoM,RizviAA,SpinasGA,etal.Glucoseloweringandantidiabetogeniceffectsofincretin-basedtherapies:GLP-1analoguesandDPP-4inhibitors[J].ExpertOpinInvestigDrugs,2009,18:1495. [4]CavalotF,PetrelliA,TraversaM,etal.Postprandialbloodglucoseisastrongpredictorofcardiovasculareventsthanfastingbloodglucoseintype2diabetesm...
DPP-4抑制剂不仅能双向控制血糖,且具有降糖外的胰腺,心血管,肾脏,肝脏等多器官保护作用和抗炎作用.本文对已有的DPP-4抑制剂及其多器官保护作用进行综述,总结其优势及进一步发展的趋势,为临床用药提供参考.%Dipeptidyl peptidase Ⅳ (DPP-4) inhibitors are a new type of oral antidiabetic drugs appeared in ...
S药物与临床 Drugs and Clinic ipeptidyl peptidase-4 inhibitors: more Dthan an anti-hyperglycemia agent DPP-4抑制剂:不仅仅是一种 降糖药 广州中山大学附属孙逸仙纪念医院内分泌科刘晓丹李焱 中图分类号 R581 文献标识码 A 文章编号 1672-2809(2014)07-0026-04 ...
5. Annayya R. Aroor,James R. Sowers,Guanghong Jia,et al.Pleiotropic effects of the dipeptidylpeptidase-4 inhibitors on the cardiovascular system.Am J Physiol Heart Circ Physiol,2014,307: H477–H492. 6. Sang Ah Lee, Young Ree Kim, Eun Jin Yang...
Dipeptidyl peptidase-4(DPP-4)inhibitors are a new class of anti-diabetic drugs.Many studies have shown that DPP-4 inhibitors have a protective effect on kidney. Monotherapy or in combination with other drugs is efficacious, well tolerated, and safe in clinical application. The underlying mechanisms...
dpp-4抑制剂:不仅仅是一种降糖药 dipeptidyl peptidase-4 inhibitorsmorethan an anti-hyperglycemia agent 下载积分:2000 内容提示: 药物与临床 Drugs and ClinicS26 药品评价 2014年第11卷第7期DPP-4抑制剂改善胰岛β细胞功能,抑制胰岛α细胞分泌胰高糖素,有效降低糖尿病患者的空腹及餐后血糖,降低糖化血红蛋白水平...
[2]Ahren B.Emerging dipeptidyl peptidase-4 inhibitors for the treatment of diabetes[J].Expert Opin Emerg Drugs,2008,13(4):593-607. [3]Wang Q,Li L,Xu E,et al.Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells[...
drugs enabling effective glycemic control in type 2 diabetes mellitus(T2DM) patients. The genes associated with β-cell function and apoptosis are involved in the therapeutic effect of DPP-4 inhibitors. This review summarizes the research progress on pharmacogenetic information of DPP-4 Inhibitors on ...
参考文献:http://www.easdvirtualmeeting.org/resources/use-of-the-japanese-health-insurance-claims-database-to-assess-durability-of-dpp-4-inhibitors-in-patients-with-diabetes-comparison-with-other-anti-diabetic-drugs--2