Fluconazole is cleared primarily by renal excretion as unchanged drug. There is no need to adjust single dose therapy for vaginal candidiasis because of impaired renal function. In patients with impaired renal function who will receive multiple doses of DIFLUCAN, an initial loading dose of 50 mg ...
Fluconazole is primarily cleared by renal excretion as unchanged drug. Because elderly patients are more likely to have decreased renal function, care should be taken to adjust dose based on creatinine clearance. It may be useful to monitor renal function. (SeeCLINICAL PHARMACOLOGYandDOSAGE AND ADMIN...
People with renal problems should prevent applying Diflucan as well; This drug can become a potential CYP34A4 and CYP2C9 inhibitor. Patients who used other medications having the same effects have to go through tests before starting to administer Diflucan; People with lactose intolerance, Lapp lac...