Day100 Score predicts moderate-severe cGVHD, transplant mortality, and survival after hematopoietic cell transplantation - ScienceDirectElisabetta MetafuniIrene Maria CavattoniTeresa LamparelliAnna Maria RaiolaAnna GhisoFederica GalavernaFrancesca Gualandi...
Additional findings from the study showed that among patients treated at the 0.3 mg/kg dose, 55% experienced a clinically meaningful improvement in symptoms, as measured by at least a seven-point decrease in the modified Lee chronic GVHD Symptom Scale score. ...
“Eighty-seven percent of patients experienced improvement compared with baseline,” Wolff noted. Moreover, 73% of patients experienced improved mLSS skin thickened score vs baseline, “underlying the crucial importance of capturing patient-reported outcomes in this patient population,” he said. “Symp...
” Wolff noted. Moreover, 73% of patients experienced improved mLSS skin thickened score vs baseline, “underlying the crucial importance of capturing patient-reported
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) may be curative, but is associated with significant morbidity and mortality. Chronic graft-versus-host disease (cGvHD), characterized by inflammation and fibrosis of multiple target organs, considerably contributes to the morbidity and mortality...
In this issue of Blood, Jacobsohn et al report that 2 simple and reproducible assess-ment tools, the National Institutes of Health (NIH) composite skin score and the Lee skin symptom scale, are powerful predictors of severity and prognosis of skin GVHD....
In a model adjusted for gender, age, time since transplant, donor type and conditioning regimen, subjects with cGVHD were more likely to report adverse general health, functional impairments, activity limitation, pain and to score in the lowest 10% of population norms on the BSI compared to ...
S1624 A DAY 100 LAB-SCORE PREDICTS EXTENSIVE CGVHD, OVERALL SURVIVAL AND TRANSPLANT-RELATED MORTALITY AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION: FINAL ANALYSISdoi:10.1097/01.HS9.0000564744.69369.fcMetafuni, E.Cavattoni, I.Lamparellli, T.
Additional endpoints include Duration of Response (DOR), corticosteroid (CS) dose reductions, Failure Free Survival (FFS) and Lee Symptom Scale (LSS) score. Results 17, 16, and 21 pts enrolled in C1, C2, and C3. As of 8Mar19, median duration of follow up was 112, 97 and 64 weeks ...
cGVHD of skin: simple tools, great advances.In this issue of Blood, Jacobsohn et al report that 2 simple and reproducible assessment tools, the National Institutes of Health (NIH) composite skin score and the Lee skin symptom scale, are powerful predictors of severity and prognosis of skin ...