例如低聚果糖,这是一种不能被人体消化的膳食纤维,却能成为Akkermansia阿克曼菌的食物,促进阿克曼菌在人体内的定植。 增加Akkermansia muciniphila水平的补充剂 当然,对于缺乏Akkermansia的人来说,仅仅通过食物营养来提高Akkermansia阿克曼菌的水平可能很具挑战性。确保肠道中阿克曼菌数量的一种简单方法是每天服用Akkermansia益...
Akkermansia muciniphila (A. muciniphila), an intestinal symbiont colonizing in the mucosal layer, is considered to be a promising candidate as a probiotics. Most of the current researches focus on th...
muciniphila GP01 to APP/PS1 mice not only affected the gut itself (intestinal barrier integrity, [112]) but also decreased Aβ deposition and led to improved performance in the Y-maze test. While in PD, several reports exist about increased Akkermansia levels [113], a clear conclusion for ...
Cross-talk between the gut microbiota and the host immune system regulates host metabolism, and its dysregulation can cause metabolic disease. Here, we show that the gut microbe Akkermansia muciniphila can mediate negative effects of IFNγ on glucose tol
许多研究表明,Akkermansia.muciniphila(A.muciniphila)的定植可降低肠道屏障的通透性,有效地防止慢性低度炎性反应的发生,并且与机体糖代谢、脂代谢以及氨基酸代谢密切相关。糖尿病、肥胖等代谢性疾病患者体内的A.muciniphila丰度下降,补充后代谢状态改善。正确地认识A.muciniphila与代谢疾病的相关性及其发挥作用的机制,有...
muciniphila supplementation slightly decreased body weight (−2.27 ± 0.92 kg, P = 0.091) compared to the placebo group, and fat mass (−1.37 ± 0.82 kg, P = 0.092) and hip circumference (−2.63 ± 1.14 cm, P = 0.091) compared to ...
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The present invention relates to an Akkermansia muciniphila SNUG-61027 strain (Accession No. KCTC 13530BP), and a pharmaceutical composition and a functional health food for suppressing appetite or preventing, ameliorating or treating metabolic diseases, comprising the strain, the culture medium or B...
Ever since Akkermansia muciniphila was discovered and characterized two decades ago, numerous studies have shown that the lack or decreased abundance of this commensal bacterium was linked with multiple diseases (such as obesity, diabetes, liver steatosis, inflammation and response to cancer immunotherapi...
Amyloid β-protein (Aβ) is widely accepted as a key biomarker for AD. Metabolic syndromes, including obesity and insulin resistance, are key high risk factors for AD. Akkermansia muciniphila (Akk), the only representative human gut microbe in the genus Verrucomicrobia, can prevent the weight ...