medwireNews: Conventional criteria for diagnosing melanoma may not be accurate in children and adolescents, suggest results published in the Journal of the American Academy of Dermatology. A checklist of symptoms known as ABCDE — Asymmetry, Border irregularity, Color variegation, Diameter (>6 mm),...
Background: Retinoic acid-inducible gene-I (RIG-I) is a cytoplasmic protein that recognizes viral double-stranded RNA to induce the type I interferon (IFN) response. In human keratinocytes, RIG-I is induced by IFN-gamma and tumor necrosis factor-alpha stimulation, and is abundantly expressed ...
Objective: To develop skin self-examination skills by improving the use of the ABCDE criteria by those at risk of developing melanoma. Design: Ten single- sex groups of 10 unrelated adults received a knowledge-based intervention followed by skills training. Setting: Classroom in the ambulatory ...
The clinical recognition of melanoma in its early phases of progression is exceedingly important since the total surgical removal of such lesions is almost invariably curative. When the clinical...doi:10.1007/978-3-540-35106-1_2A.W. Kopf