Identified on Urine Ketones, but not on Serum Ketone assays (typically for Beta-Hydroxybutyrate) Beta-Hydroxybutyrate (78%) Hydroxyacid formed via Beta-Hydroxybutyrate dehydrogenase (and NADH) Concurrent Lactic Acidosis increases the ratio of Beta-Hydroxybutyrate to Acetoacetate Not identified on Urinalysis...
Background Ketones, including beta hydroxybutyrate (BHB), are produced in conditions of negative energy balance and decreased glucose utilization. Serum BHB concentrations in cats are poorly characterized in diseases other than diabetes mellitus. Hypothesis Serum BHB concentrations will be increased in ...
2. Urinary ketones were estimated using the nitroprusside reaction that has been known to provide a semi-quantitative estimation of acetoacetate and acetone levels but does not recognize the presence of β-hydroxybutyrate, which is the main ketoacid in DKA 3. The scope of this study did not ...
Beta-Hydroxybutyrate or Ketonesare produced by the liver when the body is fasting or going through prolonged exercise. Ketones use the fat in the body to produce fuel for energy. Ketone bodies are able to create much greater amounts of energy than glucose which is the bodies primary fuel sour...
Ablation of ARNT/HIF1beta in liver alters gluconeogenesis, lipogenic gene expression, and serum ketones. Cell Metab 2009;9:428-39.Wang XL, Suzuki R, Lee K, Tran T, Gunton JE, Saha AK, Patti ME, Goldfine A, Ruderman NB, Gonzalez FJ, Kahn CR (2009) Ablation of arnt/hif1beta in ...
KetonesSerum metabolitesBiomarkersAmyotrophic lateral sclerosis (ALS), an invariably fatal neurological disorder shows complicated pathogenesis that poses challenges with respect to diagnosis as well as monitoring of disease progression. We investigated metabolite profiles in the serum of 30 patients with ALS...
The ketogenic diet (KD) has been successfully used to treat pediatric refractory epilepsy since the 1920s and is currently being investigated as an adjunct treatment for many disease states. The therapeutic efficacy of the KD results from an elevation of blood ketones. We previously reported that ...