Renal involvement is one of the important causes of morbidity and mortality in scleroderma; however, nephrotic syndrome is reported rarely in association with SSc. We present a patient with SSc who developed focal segmental glomerulosclerosis (FSGS) as a complication of scleroderma. Case presentation:...
Secondaryto:•DM(theleadingcauseofsecondarynephroticsyndrome)•SLE•Amyloidosis•Infections:HepatitisBandC,HIV,syphilis,post-streptococcal •Malignancy:multiplemyloma,Hodgkinlymphoma,solidtumor •Drugs (NSAIDs,gold,penicillamine,heavymetalsetc).•GeneralizedOdema-Thepredominantfeature-Theface,particularly...
In over 90% of children the cause of nephrotic syndrome (called primary or idiopathic nephrotic syndrome) is not known. Primary Nephrotic Syndrome is caused by four pathological types: minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy and membranoproliferati...
Tacrolimus therapy in adult-onset steroid-resistant nephrotic syndrome due to a focal segmental glomerulosclerosis single-center experience. Management of adults with steroid-resistant (SR) nephrotic syndrome due to focal segmental glomerulosclerosis (FSGS) is a challenging task. Is tacrolimus (... Raja...
In parts of the Middle East and Africa, glomerular diseases have also been linked with urogenital schistosomal infection.[17]However, tropical nephrotic syndrome due to parasitic diseases such as malaria or schistosomiasis may be non-existent. ...
withtheNS,itisimportantforhimtodeterminetheunderlyingcondition,becausethecourseandprognosiswilldependontheunderlyingdisease DISEASESASSOCIATEDWITHTHENEPHROTICSYNDROME PRIMARYRENALDISEASE Minimal-changedisease(MCD)Focalsegmentalglomerulosclerosis(FSGS)Membranousglomerulonephritis(MGN)Membranoproliferativeglomerulonephritis(MPGN)...
In nephrotic syndrome the glomerular filtration barrier fails to retain protein leading to proteinuria, hypoalbuminaemia and oedema. In childhood, most cases are idiopathic and treatment with steroids leads to complete remission of symptoms. The clinical course of the disease is characterized by relapse...
Complete remission of the nephrotic syndrome due to focal glomerular sclerosis achieved with low density lipoprotein adsorption alone. 来自 国家科技图书文献中心 喜欢 0 阅读量: 20 作者: K Yokoyama,S Sakai,Y Yamaguchi,Y Suzuki,F Hinoshita,S Hara,A Yamada,Y Ogura,Y Kawaguchi,O Sakai 展开 ...
FSGS: Focal segmental glomerular sclerosis MCN: Minimal change nephropathy MN: Membranous nephropathy MPGN: Membranoproliferative NELL-1: Neural epidermal growth factor-like 1 protein NS: Nephrotic syndrome PLA2R: Phospholipase A2 receptor PNS: Paraneoplastic nephrotic syndrome THSD7A: Thrombos...
The recent developments in the genetics of nephrotic syndrome/FSGS have focused on the Glomerular Filtration Barrier as it is the target of injury in these syndromes. The Glomerular Filtration Barrier (GBM) separates the blood from the urinary spaces. It selectively permits the ultrafiltration of ...