Low-molecular-weight heparins (LMWHs), for example, dalteparin, enoxaparin, among others, are anticoagulants. These drugs are used in the prophylaxis of venous thromboembolic disease (VTE) on acute or elective admission to the hospital, and they are used in the treatment of deep vein thromboses...
The clinical implications of these drugs during pregnancy are mainly related to their action on the placenta, because of the presence of specific molecular and cellular targets, particularly at the trophoblast-endometrial interface. As well as for the prevention and treatment of thromboembolism, LMWH ...
For drugs to be considered bioequivalent, the activity of each drug must be the same when measured at a given dose. “LMWHs have significantly different pharmacokinetic patterns when comparing activated partial thromboplastin time (APTT), thrombin clotting time (TCT), Heptest, anti-IIa activity ...
Antithrombin Drugs: LMWH, Unfractionated Heparin, Direct Thrombin Inhibitorsblood procoagulant moleculesplatelet activationthrombinfluid‐phase fibrinogenplatelet activationunfractionated heparinantithrombin action of UFHbivalirudinTIMI myocardial perfusion grade
The main adverse reactions of molecular targeted antitumor drugs include? A. Skin toxicity: skin rash, hand foot skin reaction or syndrome, etc. B. Adverse reactions of digestive system: diarrhea, nausea, vomiting, loss of appetite, etc. C. Cardiovascular toxicity: hypertension, decreased left...
LMWH不同 低分子肝素结构的不同对临床的指导意义 低分子肝素抗凝机制 3 低分子肝素通过与抗凝血酶结合使凝血因子Xa和凝血因子IIa失活而起到抗凝作用 ATIIIATIII 低分子肝素以及超低分子肝素 IIa 使Xa失活的活性更强，而且对凝血因子IIa的作用较小,依诺肝素抗Xa/抗IIa比=3~4:1 肝素（普通肝素）ATIII IIa 使...
Background: In spite of using anticoagulant drugs such as unfractionated heparin (UFH) and low molecular weight heparin (LMWH) in the treatment of acute is... R. A. Alfazli,A Janati,S. A. Karvigh,... - Caryologia -Firenze- 被引量: 31发表: 2003年 Use of Low-Molecular-Weight Hepari...
P-098: LMWH as drugs of choice as anticoagulant therapy in cancer patientsdoi:10.1016/S0049-3848(17)30196-2Vorobev, A.V.Khamani, I.V.Solopova, A.G.ESThrombosis Research
Physicians should be aware of DIP as a potential neurological complication after BMT to avoid further administration of drugs that could aggravate symptoms.doi:10.1097/00001721-199604000-00052Toh, C. H.Craig, A.Blood Coagulation & Fibrinolysis
A method to induce microthrombi in small mesenteric vessel (15-25 microns) has been developed to investigate antithrombotic drugs and to study platelet reactions. Mesenteric injuries are induced in the vascular system of Wistar rats with an argon laser. The laser beam induced formation of the ...