Use requires patient monitoring, to be administered only by experienced personnel who are not actively engaged in the procedure or surgery; in non-intubated and/or non-mechanically ventilated patients, appropriate equipment and qualified personnel should be immediately available to use appropriate equipment...
Serious ketamine side effects include:slow heart rate, weak or shallow breathing; or a light-headed feeling, like you might pass out; jerky muscle movements that may look like convulsions; painful or difficult urination, increased urination, loss of bladder control, blood in your urine....
There are no adequate and well-controlled studies of ketamine in pregnant women. In animal reproduction studies in rats developmental delays (hypoplasia of skeletal tissues) were noted at 0.3 times the human intramuscular dose of 10 mg/kg. In rabbits, developmental delays and increased fetal resorpt...
A number of studies have shown that acuteketamineuse results in impairment of both working and episodic memory; it appears that these effects are greater in men than in women[259–261]. Long-term ketamine use is also associated with deficits of both long- and short-term memory[259,262]. ...
However, ketamine evokes side effects such as sedation, as well as transient perceptual disturbances that resemble those of a psychotic-dissociative-state11,12. Even though these side effects are more pronounced in men than in women13, to date, there is no evidence of gender being a significant...
(FDA MedWatch definition) when the patient outcome is: * death * life-threatening * hospitalisation * disability * congenital anomaly * requires intervention to prevent permanent impairment or damage In a retrospective study of 50 patients, 7 men and 4 women aged 23−65 years ...
A double-blind controlled trial based on 140 women undergoing abortus provocatus was employed to study whether the frequency of side effects after administration of the anaesthetic Ketalar®(ketamine) could be reduced by a concurrent dose of Rohypnol® (flunitrazepam). The control group was given...
Both Barnett and Sanacora agreed that it was difficult to know whether the drug played any role in a study this size and said that larger studies were needed to tease out any serious safety signals. Among the participants, women and younger adults tended to have strongertreatment effects than...
8. Use In Specific Populations 8.1 Pregnancy Risk Summary There are no adequate and well-controlled studies of Ketamine Hydrochloride Injection in pregnant women. In animal reproduction studies in rats, developmental delays (hypoplasia of skeletal tissues) were noted at 0.3 times the human intramuscul...
Optimizing the use of ketamine to reduce chronic postsurgical pain in women undergoing mastectomy for oncologic indication: study protocol for the KALPAS multicenter randomized controlled trial Jing Wang Lisa V. Doan Raven Perez Trials(2024)