形成鲜明对照的是密苏里州圣路易斯的Razia Tajwar、John E. Tavis等却成功了,在我们倍感沮丧的8月份,他们的题为“Predicted structure of the hepatitis B virus polymerase reveals an ancient conserved protein fold”文章被Protein Sci 接受并于10月底发表了(doi: 10.1002/pro.4421)。原文图2. Models for the ...
形成鲜明对照的是密苏里州圣路易斯的Razia Tajwar、John E. Tavis等却成功了,在我们倍感沮丧的8月份,他们的题为“Predicted structure of the hepatitis B virus polymerase reveals an ancient conserved protein fold”文章被Protein Sci 接受并于10月底发表了(doi: 10.1002/pro.4421)。 原文图2. Models for the c...
[5] Summers J, O'Connell A, Millman I. Genome of hepatitis B virus: restriction enzyme cleavage and structure of DNA extracted from Dane particles. Proc Natl Acad Sci U S A. 1975 Nov;72(11):4597-601. doi: 10...
[1] Summers J, O'Connell A, Millman I. Genome of hepatitis B virus: restriction enzyme cleavage and structure of DNA extracted from Dane particles. Proc Natl Acad Sci U S A. 1975 Nov;72(11):4597-601. [2] Galibert, ...
,病毒性肝炎(病原学),Hepatitis A Virus (HAV;甲型肝炎病毒),Heparnavirus; Picornaviridae Virus Structure: Unenveloped, symmetric RNA virus,HAV, Gene variation 变异小,各病毒株之间同源性80% HAV有7个基因型;人类HAV有、基因型 Serotype:只有一个抗原抗体系统,Genome structure,p1,p2,p3,5NC,Coding region...
[8]MENG Z, CHEN Y, LU M. Advances in targeting the innate and adaptive immune systems to cure chronic hepatitis B virus infection[J]. Front Immunol, 2019, 10: 3127. DOI: 10.3389/fimmu.2019.03127. [9]RYBICKA M, BIELAWSKI KP. Recent advances in understanding, diagnosing, and treating hepat...
在第75届美国肝病研究学会(AASLD)年会上,广西医科大学第一附属医院江建宁教授团队在乙型肝炎病毒感染相关肝细胞癌(HBV-HCC)、HBV抗病毒治疗领域共3项研究成果被大会收录,其中一项入选大会口头报告。该项研究成果揭示了HBV整合事件对长期抗病毒治疗后HBV-HCC临床指标及宿主染色体结构的影响。另2项入选壁报交流,展示了中国...
[21]KLUMPP K, LAM AM, LUKACS C, et al. High-resolution crystal structure of a hepatitis B virus replication inhibitor bound to the viral core protein[J]. Proc Natl Acad Sci U S A, 2015, 112(49): 15196-15201. DOI: 10.1073/pnas.1513803112. ...
HBV分子生物学 HBV分子生物学 乙型肝炎病毒(HEPATITISBVIRUS)形态结构:乙肝患者血清中发现3种相关颗粒¤小球形颗粒:HBsAg不含核酸¤管形颗粒:小球形颗粒串连成(这两种颗粒均由与病毒外壳相同的脂蛋白乙型肝炎表面抗原组成,不含核酸,故没有传染性。)¤大球形颗粒:为完整的病毒颗粒,具传染性(DANE颗粒):DNA、...
[6]D RING B, L TTEKE T, GEYER J, et al. The SLC10 carrier family: Transport functions and molecular structure[J]. Curr Top Membr, 2012, 70: 105-168. [7]SLIJEPCEVIC D, KAUFMAN C, WICHERS CG, et al. Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding ...