Definition Hayflick limit is defined as the specific number of proliferations that a primary human cell can perform in culture. After this limit has been reached, the so‐called replicative or cellular senescence occurs. Ageing Steroid Hormone Receptor Defects, Molecular BasisDefinitionHayflick limit ...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook Hay·flick (hā'flik), Leonard, 20th-century U.S. microbiologist. See:Hayflick limit. Farlex Partner Medical Dictionary © Farlex 2012 Want to thank TFD for its existence?Tell a friend about us, add a ...
during which the vast majority of cells which had moved past senescence die. The few cells which can pass these barriers are immortalized. Several studies indicate that the Hayflick's limit is driven by the length of the telomeres, which are positioned at the ends of the chromosomes and are ...
Synonyms Hayflick number irreversible replicative senescence mortality stage 1 Definition The term Hayflick limit refers to the fact that the maximum number of cell divisions of a certain cell population is genetically fixed such that aging cells become non-dividing (senescent) at last. This ...