[4]Ding WY, Koziell A, McCarthy HJ, et al. Initial steroid sensitivity in children with steroid-resistant nephrotic syndrome predicts post-transplant recurrence. J Am Soc Nephrol 2014; 25:1342. [5]Pascual J, Mezrich JD, Djamali A, et al. Alemtuzum...
种组织学病变,而非一种疾病,其是成人和儿童肾病综合征常见的基础病变,特别是在美国、巴西和许多其他国家[参考文献1、Haas M, Meehan SM, Karrison TG, Spargo BH. Changing etiologies of unexplained adult nephrotic syndrome: a comparison of renal biopsy findings...
3. Fervenza FC. A patient with nephrotic-range proteinuria and focal global glomerulosclerosis. Clin J Am Soc Nephrol 2013; 8:1979. 4.Hommos MS, Zeng C, Liu Z, et al. Global glomerulosclerosis with nephrotic syndrome; the clinical importance of age adjustment. Kidney Int 2018; 93:1175. 问...
SIM J J, SMOYER W E, SCHACHTER A D. Minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are a spectrum of a single disease within immune-mediated nephrotic syndrome[J/OL]. Kidney360, 2024. [2024-7-9].https://journals.lww.com/kidney360/citation/9900/minimal_change...
参考文献 SIM J J, SMOYER W E, SCHACHTER A D. Minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are a spectrum of a single disease within immune-mediated nephrotic syndrome[J/OL]. Kidney360, 2024. [2024-7-9].https://journals.lww.com/kidney360/citation/9900/minim...
1. Carraro M, Caridi G, Bruschi M, et al. Serum glomerular permeability activity in patients with podocin mutations (NPHS2) and steroid-resistant nephrotic syndrome. J Am Soc Nephrol 2002; 13:1946. 2. Pelletier JH, Kumar KR, Engen R, et al. Recurrence of nephrotic syndrome following kidne...
7.Ramachandran R, Kumar V, Rathi M, et al. Tacrolimus therapy in adult-onset steroid-resistant nephrotic syndrome due to a focal segmental glomerulosclerosis single-center experience. Nephrol Dial Transplant 2014; 29:1918. 8.KDIGO. KDIGO Clinical Practice Guideline for Glomerulonephritis. Kidney Int...
FSGS被发现是遗传性肾病综合征中最常见的病理类型,随着基因检测的普及和检测费用的降低,目前已知致病基因已超过50个[2],有研究发现在25岁前患激素抵抗型肾病综合征(steroid-resistant nephrotic syndrome, SRNS)家系中有29.5%发现了单基因变异[3],主要与编码足细胞功能或结构蛋白的基因突变相关。遗传性FSGS可存在于儿...
Rituximab for childhood⁃onset, complicated, frequently relapsing nephrotic syndrome or steroid⁃ dependent nephrotic syndrome: a multicentre, double⁃blind, randomised, placebo⁃controlled trial. Lancet, 2014, 384 ( 9950 ) : 1273⁃1281. 4 Shalhoub JR. Pathogenesis of lipoid nephrosis: a ...
FSGS（局灶节段硬化性肾小球肾炎)也就是慢性肾小球肾炎“肾病综合征Nephrotic Syndrome”的病理诊断。慢性肾炎早期应该针对其病理类型给予相应的治疗，慢性肾脏功能衰竭，一的般都有白血球减少。严重者可用粒细胞集落刺激因子(G-CSF)即是Neupogen等针剂治疗，效果不错，但要长期用，费用太大。(有贫血者亦...