目前人们对于FSGS仍有太多未知,即使是原发性FSGS,异质性也非常大,且FSGS的治疗存在诸多困境,包括频繁复发,激素依赖,激素抵抗和快速进展为终末期肾病(End stage kidney disease, ESKD)。南昌大学第二附属医院徐承云教授在本文中综述了遗传性FSGS的诊治进展。 FSGS的分类 根据病理组织形态分类的经典哥伦比亚分型法将FSGS分...
2. Haas M, Yousefzadeh N. Glomerular tip lesion in minimal change nephropathy: a study of autopsies before 1950. Am J Kidney Dis 2002; 39:1168. 3. Stokes MB, Markowitz GS, Lin J, et al. Glomerular tip lesion: a distinct entity within the minimal change disease/focal segmental glomerulosc...
ZHANG Jiong,WANG Jinquan National Clinical Research Center of Kidney Disease,Jinling Hospital,Nanjing Medical University, Nanjing 210016,China ABSTRACT Focal segmental glomerulosclerosis ( FSGS) is a common glomerular disease leading to end stage renal disease, and podocyte injury is the main cause of ...
RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook ACTN4 (redirected fromFSGS) Acronyms ACTN4 A gene on chromosome 14q24.1 that encodes an actin-binding bundling protein expressed in various cells, playing different roles in each. In non-muscle cells, the cytoske...
GLOMERULAR-DISEASEOUTCOMESCHILDRENIntroductionFocal segmental glomerulosclerosis (FSGS) is a leading cause of kidney disease and can progress to end stage kidney disease (ESKD). An overview of symptoms and impacts of the disease experienced will help inform the selection or development of fit-for-...
Thromboxane, excreted in the urine in increased amounts in glomerular, vascular and tubulo-interstitial diseases, is considered to originate from the kidney. The localization of thromboxane synthase, a key enzyme of arachidonic acid metabolism, was studied in the human kidney by immunohistology using...
系统标签: fsgs低浓度发性激素回顾对照 硕士学位论文低浓度他克莫司联合激素治疗特发性FSGS的回顾性对照研究刘宝莲指导教师赵洪雯副教授导师组成员彭侃夫教授、刘宏教授、张克勤教授培养单位陆军军医大学第一附属医院肾科申请学位类别临床医学硕士专业学位专业名称内科学(肾脏病)论文提交日期2019年3月论文答辩日期2019年5月答辩...
Mutations in α-actinin 4 (ACTN4) are linked to familial forms of focal segmental glomerulosclerosis (FSGS), a kidney disease characterized by proteinuria due to podocyte injury. The mechanisms underlying ACTN4 mutant-associated FSGS are not completely understood. Although α-actinins are better ...
TRPC6 canonical transient receptor potential-6 channel Keywords Chronic kidney disease TRPC6 suPAR TNF Integrin Podocin Sorry, something went wrong. Please try again and make sure cookies are enabledCited by (0)1 Present address: National Institute of Diabetes and Digestive and Kidney Disease, Nation...
Microcosmic dysplastic kidney disease CD40L: CD40 ligand rFSGS: Recurrent FSGS LIFRβ: Leukemia inhibitory factor-β CRLF-1: Cytokine receptor-like factor-1 rCASK: Recombinant-CASK WT1: Nephroblastoma protein PEC: Glomerular wall epithelial cell ...